DLF Science Advisory Board Spotlight
Dan Lewis Foundation | Summer 2023

Michael C. Crair, Ph.D., serves on the Science Advisory Board for the Dan Lewis Foundation and on its Board of Directors. Dr. Crair has been instrumental in developing the research agenda the Dan Lewis Foundation has established. He recently worked with members of the Science Advisory Board to select the first winner of the Dan Lewis Foundation Award, an award selecting a post-doctoral neuroscientist working in the field of brain regeneration.


Michael C. Crair is the William Ziegler III Professor in the Department of Neuroscience, Professor of Ophthalmology & Visual Science, and Vice Provost for Research at Yale University. Dr. Crair obtained his doctoral degree in physics from the University of California, Berkeley, and did postdoctoral training in physics and neuroscience at Kyoto University and Kyoto Prefectural Medical School in Japan and in neuroscience at the University of California, San Francisco. He was a faculty member at Baylor College of Medicine in Houston, Texas, before coming to Yale as a member of the Department of Neuroscience in 2007. He has directed Yale’s Vision Core Program, the Graduate Program in Neuroscience, was Deputy Chair of the Department of Neuroscience from 2015-2017, then Deputy Dean for Scientific Affairs (Basic Science Departments) at the School of Medicine from 2017-2020 when he became the Vice Provost for Research at Yale University.


Dr. Crair maintains an active research program that develops and employs advanced imaging techniques to examine the basic mechanisms that mediate brain circuit development. He has made fundamental contributions to our understanding of neural activity in the developing brain by demonstrating that early spontaneous neuronal activity is an essential part of normal brain development. He is currently exploring the mechanisms by which this activity is generated and how it shapes brain circuit development. He has been awarded numerous honors for his research and teaching, including the Esther A. and Joseph Klingenstein Foundation Fellowship Award in the Neurosciences, the Marc Dresden Excellence in Graduate DLF Science Advisory Board Spotlight Education Award, and a NARSADSidney R. Baer Jr. Foundation Young Investigator Award. He has also been named an Alfred P. Sloan Foundation Research Fellow, a John Merck Fund Scholar, and the March of Dimes Foundation’s Basil O’Connor Fellow. 

The word arpah is written in blue letters on a white background.

ARPA-H Announcement Seeks Research Projects in Brain Regeneration

By Dan Lewis Foundation • July 31, 2025
On July 10, 2025, the Advanced Research Projects Agency for Health (ARPA-H) announced a major initiative titled Functional Repair of Neocortical Tissue or FRONT. The announcement states “FRONT will pioneer a curative therapy for the more than 20 million adults in the US living with chronic neocortical brain damage from neurodegeneration, stroke, trauma, and other causes, which costs the country an estimated $800 billion per year. Worldwide, more than 200 million people live with debilitating after-effects of brain damage.”  A set of informational meetings about this program and a due date for outlines of potential proposals have been set for August. Full proposals are due by September 25, 2025. Complete instructions, specifications, and expectations are delineated in the ARPA-H FRONT announcement. The FRONT announcement includes a clear expectation that the successful brain regeneration methods that are discovered will be used in clinical trials with persons with brain injury by the fifth year of the program. The DLF lauds ARPA-H for initiating this program. We are discussing possibilities for playing a supportive role as proposals develop. This exciting program is congruent with the original overarching goals of the DLF and confirms the validity of its mission.
Photo of Dr. Justin Burrell

2025 DLF Prize Awarded to Justin Burrell, Ph.D.

By Dan Lewis Foundation • July 31, 2025
Dr. Burrell is a translational neuroengineer in the Departments of Neurosurgery and Oral & Maxillofacial Surgery at the University of Pennsylvania. His research integrates advanced neural repair strategies with clinical translation, focusing on axon protection, nerve fusion, and engineered neural tissue for neurotrauma recovery. Dr. Burrell has led the development of multiple first-in-field innovations—including the first large-animal model of nerve fusion, delayed axonal fusion protocols, and the first orally active axonal protectants—positioning him as a recognized leader in regenerative neurotechnologies. He is co-founder of Neurostorative LLC and plays a central role in several other platforms aimed at neural reconnection, long-term preservation, and bio-integrated prosthetic systems.